1. Develop a research question. PICO or other question framing devices can be used to clarify your question.
2. Register your protocol (https://www.crd.york.ac.uk/PROSPERO/)
2. Define inclusion and exclusion criteria
3. Run a database search to locate studies and document your strategies for each database.
4. Select studies for inclusion
5. Assess quality of studies
6. Extract data.
7. Analyze and present results
8. Interpret results
9. Update the review as needed
